The Chronic Lymphocytic Leukemia Channel on VJHemOnc is an independent medical education platform, supported with funding from AstraZeneca (Diamond), AbbVie (Platinum), BeOne Medicines (Silver) and Lilly (Silver). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.
The Lymphoma Channel on VJHemOnc is an independent medical education platform, supported with funding from AstraZeneca (Diamond), BMS (Gold), Johnson & Johnson (Gold), Takeda (Silver) and Galapagos (Bronze). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.
EHA 2024 | Insights into ongoing research on BTK degraders for lymphoid malignancies
Alexey Danilov, MD, PhD, City of Hope, Duarte, CA, discusses the emergence of BTK degraders in the treatment landscape of lymphoid malignancies. Prof. Danilov highlights the results from an ongoing Phase I trial (NCT05131022) of NX-5948 in heavily pretreated patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL). This agent had a promising 70% response rate and an impressive safety profile with no major adverse events reported. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.
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