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SOHO 2025 | Novel therapies and clinical trial approaches for Richter’s transformation

Catherine Coombs, MD, UC Irvine Health, Orange, CA, comments on the challenges and potential treatment options for Richter’s transformation (RT) in chronic lymphocytic leukemia (CLL), emphasizing the importance of enrolling patients in clinical trials. She notes that RT is a serious complication and further highlights combinations and novel agents being explored to improve upon the standard of care. This interview took place at the 13th Annual Meeting of the Society of Hematologic Oncology (SOHO 2025) in Houston, TX.

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