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ASH 2025 | Results of a Phase II trial of pirtobrutinib plus venetoclax in previously treated WM

Jorge Castillo, MD, Dana-Farber Cancer Institute, Boston, MA, discusses the results of a Phase II study (NCT05734495) of pirtobrutinib plus venetoclax in previously treated Waldenström’s macroglobulinemia (WM). Dr Castillo highlights that the study met its primary endpoint with 15 out of 27 patients achieving a very good partial response or complete response. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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