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SOHO 2025 | Switching to venetoclax-based therapy after progression on covalent BTKis in CLL: expert opinion

Gianluca Gaidano, MD, PhD, University of Eastern Piedmont, Vercelli, Italy, briefly discusses the potential benefits of using venetoclax-based regimens to treat patients with chronic lymphocytic leukemia (CLL) who progress on covalent BTK inhibitors. He also advises against using venetoclax-based regimens in patients with p53-disrupted CLL. This interview took place at the 13th Annual Meeting of the Society of Hematologic Oncology (SOHO 2025) in Houston, TX.

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