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EHA 2024 | Tafasitamab plus lenalidomide post-CD19 CAR-T is associated with poor outcomes in LBCL

Vincent Camus, MD, PhD, University of Rouen, Rouen, France, discusses outcomes for patients with large B-cell lymphoma (LBCL) who are treated with tafasitamab plus lenalidomide following CD19-targeting CAR-T therapy. The study found poor outcomes with short progression-free survival (PFS). Comparisons with other post-CD19 CAR-T treatments showed no significant differences in outcomes. However, patients who relapsed more than six months post-CAR-T therapy experienced slightly improved outcomes. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Honoraria: Incyte, AbbVie, Astra Zeneca, BMS, Ideogen, Janssen, Kiowa Kirin, Kite/Gilead, Lilly, Novartis, Octapharma, Pfizer, Pierre Fabre, Sanofi, Takeda.