The Myeloproliferative Neoplasms Channel on VJHemOnc is an independent medical education platform, supported with funding from Takeda (Gold) and Kartos Therapeutics, Inc. (Bronze). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.
Texas MPN Workshop 2021 | Driver mutations implicated in MPNs
Stephen Oh, MD, PhD, Washington University School of Medicine, St. Louis, MO, discusses driver mutations for myeloproliferative neoplasms (MPNs) such as JAK2, CALR, and MPL, all of which result in some degree of activation of the JAK/STAT signalling pathway. Dr Oh also talks on the impacts of secondary mutations such as splicing mutations that play a role in the pathogenesis of MPNs, highlighting their prognostic implications. This interview took place at the Texas MPN Workshop: Second Annual Workshop and Meeting in 2021.
