Jorge Castillo, MD, Dana-Farber Cancer Institute, Boston, MA, comments on the promising results of a Phase II study (NCT05734495) evaluating the combination of pirtobrutinib and venetoclax in previously treated patients with Waldenström’s macroglobulinemia (WM). Dr Castillo highlights that the study has shown a 65% very good partial response (VGPR) rate in the first 16 patients enrolled and that the combination has been well-tolerated with no unexpected side effects. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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