Sabina Chiaretti, MD, PhD, University of Rome, Rome, Italy, gives an overview of a recent publication that highlights important considerations when treating patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL). Dr Chiaretti notes the importance of measurable residual disease (MRD) monitoring and addressing CNS relapse, suggesting that CAR-T and subsequent allogeneic stem cell transplant may be a viable option for these patients. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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