The Lymphoma Channel on VJHemOnc is an independent medical education platform, supported with funding from AstraZeneca (Diamond), BMS (Gold), Johnson & Johnson (Gold), Takeda (Silver) and Galapagos (Bronze). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.
ASCO 2025 | The emerging role of radiation therapy in transplant-free salvage of R/R cHL in pediatric patients
In this video, Sarah Milgrom, MD, University of Colorado School of Medicine, Aurora, CO, briefly comments on the emerging role of radiation therapy in transplant-free salvage of relapsed/refractory (R/R) classical Hodgkin lymphoma (cHL) in pediatric, adolescent, and young adult patients. Dr Milgrom notes that recent trials have shown encouraging salvage rates with a transplant-free approach that uses systemic therapy followed by radiation therapy as consolidation in low-risk patients. This interview took place during the 2025 American Society of Clinical Oncology (ASCO) Meeting in Chicago, IL.
These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.
Transcript
For many decades the approach for salvage of relapsed and refractory classical Hodgkin lymphoma has been high-dose chemotherapy followed by autologous stem cell transplantation. However, recently several trials have shown that patients with low-risk relapsed classical Hodgkin lymphoma experience excellent salvage rates with a transplant-free approach that uses systemic therapy followed by radiation therapy...
For many decades the approach for salvage of relapsed and refractory classical Hodgkin lymphoma has been high-dose chemotherapy followed by autologous stem cell transplantation. However, recently several trials have shown that patients with low-risk relapsed classical Hodgkin lymphoma experience excellent salvage rates with a transplant-free approach that uses systemic therapy followed by radiation therapy. So radiation therapy is used as consolidation rather than transplant. So I predict that radiation therapy will be used more commonly as a part of salvage strategies going forward.
This transcript is AI-generated. While we strive for accuracy, please verify this copy with the video.
Read more...
