Lydia Scarfò, MD, Vita-Salute San Raffaele University & IRCCS San Raffaele Scientific Institute, Milan, Italy, discusses the risk of COVID-19 infection and chronic lymphocytic leukemia (CLL). Cases were collected all over the world in a retrospective study. It was found that patients with CLL did not contract COVID-19 at a higher rate than the general population, but were more likely to suffer from more severe infections. Treatment with BTK-inhibitors also displayed protective qualities. Patients who were not undergoing treatment were associated with more severe COVID-19 infections. This interview took place during the European Research Initiative on CLL (ERIC) International Virtual Meeting 2020.