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ICML 2025 | Key barriers that may prevent community centers from implementing bispecifics into their practice

Tara Graff, DO, Mission Cancer and Blood, Des Moines, IA, outlines the main barriers that may prevent community centers from implementing the administration of bispecific antibodies into their practice. From her experience, the main obstacles often revolve around physician willingness, relationships with a hospital system, and staffing, with different centers facing varying challenges. Dr Graff highlights the importance of having a team in place, including nurses, pharmacists, and advanced practitioners, to support the administration of these therapies. This interview took place during the 18th International Conference on Malignant Lymphoma (18-ICML) in Lugano, Switzerland.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Transcript

You know, it’s different for every center. I’ve worked with a number of different sites across the US and actually a couple in different countries as well, and they’re different. So sometimes it’s just the willingness of physicians to take on that lift, right? Because they might be on call more, there might be more work involved. And sometimes, you know, docs want to leave at five o’clock...

You know, it’s different for every center. I’ve worked with a number of different sites across the US and actually a couple in different countries as well, and they’re different. So sometimes it’s just the willingness of physicians to take on that lift, right? Because they might be on call more, there might be more work involved. And sometimes, you know, docs want to leave at five o’clock. They don’t want to have to be on call overnight. Other times it’s the hospital system. Even though a lot of these drugs can be administered safely in the outpatient setting, you still have to have an ability to admit to the hospital if there’s a higher grade CRS event or if there’s a fever or an infection. And so if you don’t have a relationship with a hospital system, it’s a no-go. You have to have that relationship, and it’s interesting that a number of community groups don’t have that. The hospital systems are sort of separate. They have their own hospitalists that admit patients. And so that’s a non-starter. Sometimes it’s just a matter of staffing, right? The docs want to do it, they have a hospital relationship, but they need a team. You have to have a bispecific team, whether that’s nurses, pharmacists, advanced practitioners, but you have to have a team. And so it’s not one thing. The barriers are different for different groups. Thank you.

 

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Disclosures

Consultancy: AbbVie, ADC Therapeutics, AstraZeneca, BMS, Beigene, Janssen, Genentech, Gilead/Kite, Pfizer; Advisory Board: AbbVie, Adaptive Biotechnologies, AstraZeneca, BMS, Beigene, Genmab, Incyte, Lilly; Steering committee: AbbVie, Genmab; Speaker fees: AbbVie, Beigene, Genmab.