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The Lymphoma Channel on VJHemOnc is an independent medical education platform, supported with funding from AstraZeneca (Diamond), BMS (Gold), Johnson & Johnson (Gold), Takeda (Silver) and Galapagos (Bronze). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.
ASH 2023 | Zanubrutinib in patients with B-cell malignancies who are acalabrutinib-intolerant
Mazyar Shadman, MD, Fred Hutchinson Cancer Research Center, Seattle, WA, discusses a study (NCT04116437) assessing the efficacy of zanubrutinib, a next-generation BTK inhibitor (BTKi), in patients with B-cell malignancies who are intolerant to acalabrutinib. Zanubrutinib shows efficacy without causing high-grade adverse events (AEs), making it a promising BTKi for patients who need an alternative to acalabrutinib. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Consultancy: Eli Lilly, BeiGene, Fate Therapeutics, Janssen, Kite, a Gilead Company, Bristol Myers Squibb, MorphoSys/Incyte, AstraZeneca, Pharmacyclics, Mustang Bio, Genmab, ADC therapeutics, Genentech, AbbVie, MEI Pharma, Regeneron; Research Funding: BeiGene, Bristol Myers Squibb, MorphoSys/Incyte, AstraZeneca, Pharmacyclics, Mustang Bio, Genmab, Vincerx, Genentech, AbbVie, TG Therapeutics.
