Cami-T, as many will know, is an antibody-drug conjugate [that] targets CD25 and has a toxin linker that is attached to the back, a bitter pill, if you like as cells sort of engulf that toxic payload that is attached to the back. We’ve seen very encouraging responses, particularly in patients who have failed other standard therapies, failed transplant. There have been some side effects and toxicities, but exactly how the drug is administered appears to be helping us circumvent that...
Cami-T, as many will know, is an antibody-drug conjugate [that] targets CD25 and has a toxin linker that is attached to the back, a bitter pill, if you like as cells sort of engulf that toxic payload that is attached to the back. We’ve seen very encouraging responses, particularly in patients who have failed other standard therapies, failed transplant. There have been some side effects and toxicities, but exactly how the drug is administered appears to be helping us circumvent that. We’ve seen some updated results as we’ve seen the durability and the response rates being maintained. I think that’s really the exciting part about this agent. We’re desperate for new drugs that will help patients, particularly those who fail standard treatments, including chemotherapy, transplant, brentuximab vedotin, and PD-1 blockade, and that’s really the space in which Cami-T, at this point on its own is being tested, but I think in the future will be tested in combination approaches. I think the updates that we’ve seen have been that the response rates remain high and the durability of response in some patients has been very encouraging. As I said earlier, our goal is now to optimize the administration of it to minimize the side effects.