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ASH 2024 | Outcomes of inotuzumab/blinatumomab-based treatment in pts with Ph- ALL & myeloid-type mutations

In this video, Jayastu Senapati, MBBS, The University of Texas MD Anderson Cancer Center, Houston, TX, comments on the outcomes of adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL) who possess myeloid-type mutations treated with frontline regimens containing inotuzumab and/or blinatumomab. Dr Senapati highlights that myeloid-type mutations may be associated with slightly inferior relapse-free survival and overall survival, but when treated with frontline immunotherapy-based regimens, these mutations do not necessarily lead to poor outcomes. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.

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