As with all drugs, interactions are important in our patients because our patients have many different pharmaceutical agents on board at the same time. These two drugs are slightly different. Letermovir has more interactions than maribavir, but usually with drugs that we monitor anyway, where we’re used to checking concentration by therapeutic drug monitoring, such as the immunosuppressive agents and voriconazole...
As with all drugs, interactions are important in our patients because our patients have many different pharmaceutical agents on board at the same time. These two drugs are slightly different. Letermovir has more interactions than maribavir, but usually with drugs that we monitor anyway, where we’re used to checking concentration by therapeutic drug monitoring, such as the immunosuppressive agents and voriconazole. Maribavir has few very important interactions, and for that reason, it’s easier to use. On the other hand, because of its indication, which is in resistant and refractory CMV, it is used in fewer patients as well.
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