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The Thalassemia Channel on VJHemOnc is an independent medical education platform, supported with funding from Agios (Gold). Supporters have no influence on the production of content. The levels of sponsorship listed are reflective of the amount of funding given.
EBMT 2025 | Addressing the global variability in conditioning regimens for patients with thalassemia
In this video, Mohammed Essa, MD, Ministry of National Guard Health Affairs, Riyadh, Saudi Arabia, emphasizes the need for global collaboration to harmonize treatment approaches for patients with thalassemia, specifically regarding pre-transplant conditioning regimens. This interview took place at the 51st Annual Meeting of the EBMT in Florence, Italy.
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Transcript
So the challenge here it that conditioning regimens have been variable between centers around the world. You have experience from many different continents, let’s say in East Asia, India, the Middle East, and of course in Europe and North America. Many different countries around the world use different approaches, but we always talk about myeloablative regimen versus reduced intensity conditioning regimen, especially with those patients who are complicated, who can be transplanted with pre-preparative conditioning timing like giving immunosuppressive therapy earlier on prior to transplantation in order hopefully to improve the outcome...
So the challenge here it that conditioning regimens have been variable between centers around the world. You have experience from many different continents, let’s say in East Asia, India, the Middle East, and of course in Europe and North America. Many different countries around the world use different approaches, but we always talk about myeloablative regimen versus reduced intensity conditioning regimen, especially with those patients who are complicated, who can be transplanted with pre-preparative conditioning timing like giving immunosuppressive therapy earlier on prior to transplantation in order hopefully to improve the outcome. So collaboration and different studies between different centers around the world is really necessary to harmonize the treatment.
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