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SOHO 2024 | The sequencing of therapies for R/R MCL: BTKis and novel agents

Craig Portell, MD, University of Virginia, Charlottesville, VA, discusses the sequencing of therapies for relapsed/refractory (R/R) mantle cell lymphoma (MCL). He emphasizes that treatment in this setting is dependent on prior BTK inhibitor (BTKi) exposure and notes the potential for utilizing novel agents such as CAR T-cell therapy and non-covalent BTK inhibitors. This interview took place at the Twelfth Annual Meeting of the Society of Hematologic Oncology (SOHO 2024) congress in Houston, TX.

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Disclosures

Consulting: Beigene, Janssen/Pharmacyclics, Kite, Morphopsis, TG Therapeutics, AbbVie, Merck, AstraZeneca. Research Funding: Abbvie, Merck, Acerta/AstraZeneca, Lilly/Loxo, BeiGene, SeaGen/Pfizer