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EHA 2025 | Best practices & ongoing research in supportive care for patients with hematological malignancies

In this video, Esther Oliva, MD, London North West University Healthcare NHS Trust, London, UK, briefly discusses the current best practices and ongoing research in supportive care for patients with hematological malignancies. She highlights the importance of considering alternative treatments to transfusions, investigating the role of antifungals and antimicrobials in preventing infections, and exploring the impact of the gut microbiome on patient outcomes. This interview took place at the 30th Congress of the European Hematology Association (EHA) in Milan, Italy.

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Transcript

So for supportive care we can consider transfusions for those patients that have anemia and do not have any available treatments. However, for transfusions, we must consider all available treatments that can avoid transfusions. 

As far as infections are concerned, there’s a lot of research regarding whether or not to use antifungals and prophylaxis for certain hematological malignancies before, during chemotherapy, after chemotherapy, and also the broad-spectrum antimicrobials...

So for supportive care we can consider transfusions for those patients that have anemia and do not have any available treatments. However, for transfusions, we must consider all available treatments that can avoid transfusions. 

As far as infections are concerned, there’s a lot of research regarding whether or not to use antifungals and prophylaxis for certain hematological malignancies before, during chemotherapy, after chemotherapy, and also the broad-spectrum antimicrobials. And there’s a lot of investigation on gut environment and how this impacts patient outcomes in terms of chemotherapy, infections, and overall results in the treatment of the malignancies. So, there’s a lot of research; we still don’t have definite answers, but I think we’re on our way to having novel strategies to better support patients.

 

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