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ASH 2025 | Bexobrutideg in CLL and approaching the sequencing of BTK degraders and inhibitors

In this video, Wojciech Jurczak, MD, PhD, Jagiellonian University, Krakow, Poland, briefly discusses the potential of BTK degraders, such as bexobrutideg, in chronic lymphocytic leukemia (CLL). Prof. Jurczak highlights that repeatedly blocking BTK pathways with multiple inhibitors may lead to resistance and suggests that using a BTK inhibitor followed by a BTK degrader may be a more effective approach. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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