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EHA 2024 | Moving toward a cure for cHL without chemotherapy: results of a clinical trial

Ryan Lynch, MD, Seattle Cancer Care Alliance, University of Washington, Seattle, WA, discusses the potential for treating patients with classical Hodgkin lymphoma (cHL) using a chemotherapy-free approach. The results of a small clinical trial conducted in older patients (aged over 60) with cHL who were ineligible for intensive chemotherapy demonstrated that around half of patients achieved durable remissions at a median follow-up of four years when treated with brentuximab vedotin plus nivolumab. Dr Lynch highlights that this may pave the way for chemotherapy-free treatment approaches, reducing the treatment burden of patients with the disease. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Research Funding: TG Therapeutics, Incyte, Bayer, Cyteir, Genentech, SeaGen, Rapt, Merck, Janssen; Consultancy/Honoraria: SeaGen, Foresight Diagnostics, Abbvie, Janssen, Merck.