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ASH 2023 | EP0042, an inhibitor of FLT3 & Aurora kinases, in R/R AML and MDS: insights from a Phase I/IIa trial

David Taussig, PhD, MRCP, FRCPath, The Royal Marsden NHS Foundation Trust, London, UK, presents the findings of a Phase I/IIa trial investigating EP0042, an orally bioavailable potent inhibitor of FLT3 and Aurora kinases, as a treatment for patients with relapsed/refractory (R/R) acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). Dr Taussig discusses data from the study’s dose-finding and dose-optimization cohorts, outlining the safety and efficacy of the agent. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Consultancy: Ellipses Pharma