ASH 2023 | The unmet needs in AL amyloidosis and limitations of the current SoC
Paolo Milani, MD, PhD, Amyloidosis Research and Treatment Center, Pavia, Italy, provides insights into the unmet needs for patients with light chain (AL) amyloidosis and highlights the need for an approved standard of care (SoC) for patients with advanced disease. Patients with Mayo cardiac stage IIIa disease or higher have been excluded from previous clinical trials, meaning that data to inform optimal SoC in this patient group is insufficient. Dr Milani eagerly anticipates the prospective data from several ongoing clinical trials which focus on treating advanced AL amyloidosis in a controlled setting, and hopes that with more knowledge in this space, the number of patients reaching advanced disease will decrease. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.
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Disclosures
Honoraria: Pfizer, Jannsen-Cilag
Membership on Board of Directors or advisory committee: Jannsen-Cilag, Siemens
