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iwCLL 2023 | The current SoC in Richter’s transformation and the potential role of CAR T-cell therapy

In this interview, Romain Guieze, MD, PhD, CHU Clermont Ferrand, Clermont Ferrand, France, outlines the current standard of care (SoC) for treating Richter’s transformation (RT), which is treated in the same manner as de novo diffuse large B-Cell lymphoma (DLBCL). As anti-CD19 CAR T-cell therapy has been transformative in treatment of DLBCL, Dr Guieze and his team have investigated the use of this therapy for the treatment of RT in order to elucidate how patient outcomes compare to the SoC. This interview was recorded at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.

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