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ASH 2025 | Which strategies hold promise for treating TP53-mutated MDS?

In this video, David Sallman, MD, Moffitt Cancer Center, Tampa, FL, discusses the path forward for treating TP53-mutated patients with myelodysplastic syndromes (MDS), emphasizing the unmet need for TP53-specific strategies. Dr Sallman mentions the potential of several agents, including small-molecule reactivators like rezatapopt and novel immune therapies such as bexmarilimab. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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