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ISA 2024 | Proteomic analyses of cardiac ATTR and AL amyloidosis: key findings and clinical implications

Taxiarchis Kourelis, MD, Mayo Clinic, Rochester, MN, discusses proteomic analyses of cardiac transthyretin (ATTR) and light chain (AL) amyloidosis. Using data-independent acquisition proteomics on cardiac biopsies from AL and ATTR cohorts, the study identified significant differences between advanced disease cases and those with better outcomes. This interview took place at the XIX International Symposium on Amyloidosis (ISA) in Rochester, MN.

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Research funding Pfizer