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EHA 2024 | An update on the COBRA trial: PET-response adapted treatment with brentuximab vedotin for HL

Martin Hutchings, MD, PhD, Copenhagen University Hospital, Copenhagen, Denmark, discusses the positive results of the COBRA trial (NCT03517137), a Phase II study investigating PET-response adapted treatment with brentuximab vedotin-containing regimens for advanced Hodgkin lymphoma (HL). The trial showed prolonged progression-free survival (PFS) compared to the ECHELON-1 trial (NCT01712490). This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Research Funding: Takeda, Roche and Genmab, Celgene, Novartis; Consultancy: Takeda, Roche and Genmab, Celgene, Novartis, AbbVie, AstraZeneca, Janssen, Merck, F. Hoffmann-La Roche Ltd, Bristol Myers-Squibb, Genentech, Incyte; Honoraria: Takeda, Roche and Genmab, Celgene, AbbVie, AstraZeneca, Merck, F. Hoffmann-La Roche Ltd; Membership on an Entity’s Board of Directors or Advisory Committees: Takeda, Roche and Genmab, Celgene, AbbVie, AstraZeneca, Janssen, Merck, F. Hoffmann-La Roche Ltd.