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ASH 2025 | TaZa CLL: tafasitamab and zanubrutinib in newly diagnosed CLL

Georgios Pongas, MD, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL, discusses the results of the ongoing TaZa CLL study (NCT05718869), an investigator-initiated Phase II trial investigating tafasitamab and zanubrutinib in newly diagnosed patients with chronic lymphocytic leukemia (CLL). Dr Pongas highlights the combination’s ability to achieve high overall response rates (ORR) and progression-free survival (PFS), noting that the treatment is well-tolerated. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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