Saurabh Zanwar, MD, Mayo Clinic, Rochester, MN, discusses upcoming treatments for amyloidosis, highlighting the potential role of venetoclax in combination with daratumumab for patients with the t(11;14) translocation. Additionally, trials of bispecific antibodies are yielding exciting results. Finally, the ongoing Phase III VITAL trial (NCT02312206) of birtamimab (NEOD001) in patients with stage 3B cardiac light chain (AL) amyloidosis has shown an improvement in survival and is currently accruing. This interview took place at the XIX International Symposium on Amyloidosis (ISA) in Rochester, MN.
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