So this is an oral PI3Kδ inhibitor, which had a novel study design giving the full dose of the drug for eight weeks at 20 milligrams and then a reduced dose of 2.5 daily for indefinitely until toxicity or progression. And this is highly active in relapsed/refractory follicular lymphoma patients with high overall response rate and it was rapid onset with the majority of the responses being seen by the first response assessment...
So this is an oral PI3Kδ inhibitor, which had a novel study design giving the full dose of the drug for eight weeks at 20 milligrams and then a reduced dose of 2.5 daily for indefinitely until toxicity or progression. And this is highly active in relapsed/refractory follicular lymphoma patients with high overall response rate and it was rapid onset with the majority of the responses being seen by the first response assessment. We did see some diarrhea and colitis later on and this has been known with this class of drugs, but they were reversible and manageable in the majority of patients.