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EHA 2024 | Phase II trial of obinutuzumab, alone and combined with vemurafenib, in R/R hairy cell leukemia

Enrico Tiacci, MD, University of Perugia, Perugia, Italy, discusses the findings of a multicenter Phase II trial evaluating obinutuzumab as a monotherapy and in combination with vemurafenib (a BRAF inhibitor) in patients with relapsed/refractory (R/R) hairy cell leukemia (HCL). Around half of the patients in the study responded well to obinutuzumab monotherapy, and those who did not exhibit a response were successfully salvaged with the combination therapy. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Kite/Gilead, Deciphera, Innate Pharma, Roche.