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ASH 2025 | Tafasitamab with lenalidomide in patients with relapsed central nervous system lymphoma

James Rubenstein, MD, PhD, University of California San Francisco, San Francisco, CA, discusses the interim analysis of a Phase I/II study (NCT05351593) evaluating tafasitamab in combination with lenalidomide for patients with highly refractory primary and secondary central nervous system (CNS) lymphoma. He highlights encouraging response rates and durable remissions with manageable toxicity, supporting further development of this CD19-targeted approach. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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