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IWWM-12 2024 | The use of multi-omics to understand the progression from MGUS to WM

Simone Ferrero, MD, University of Torino and Hospital “Città della Salute e della Scienza di Torino”, Torino, Italy, discusses how multi-omics studies could be used to decipher which patients with monoclonal gammopathy of undetermined significance (MGUS) may progress to Waldenström’s macroglobulinemia (WM). He mentions how the identification of prognostic markers could allow pre-emptive treatment to prevent the transformation of disease. This interview took place at the 12th International Workshop on Waldenström’s Macroglobulinemia (IWWM-12) in Prague, Czech Republic.

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Disclosures

Consultant: Janssen, EUSA Pharma, Abbvie and Sandoz; Advisory board: Janssen, EUSA Pharma, Recordati, Incyte, Roche, Astra Zeneca and Italfarmaco; Speaker’s honoraria: Janssen, EUSA Pharma, Recordati, Lilly, Beigene, Gilead and Gentili ; Research funding: Gilead, Beigene and Morphosys.