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SOHO 2025 | Stem cell transplant in 2025: latest advances, improving GvHD, and key clinical trials

Alexandra Gomez-Arteaga • 10 Sep 2025
SOHO 2025
General Axatilimab Cyclophosphamide Methotrexate ORCA-T Tacrolimus
BMT CTN 1703 BMT CTN 1801

Alexandra Gomez-Arteaga, MD, Weill Cornell Medicine, New York, NY, discusses the future of stem cell transplantation (SCT) for hematologic malignancies, highlighting three promising studies that aim to improve outcomes for patients. Dr Gomez-Arteaga highlights several novel agents and approaches being explored to enhance graft-versus-host disease (GvHD) prophylaxis, including Orca-T and axatilimab, and also shares insights into immune reconstitution outcomes following post-transplant cyclophosphamide (PTCy). This interview took place at the 13th Annual Meeting of the Society of Hematologic Oncology (SOHO 2025) in Houston, TX.

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