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EBMT 2025 | The need for early referral for transplantation in pediatric patients with non-malignant disorders

In this video, Rawad Rihani, MD, MSc, King Hussein Cancer Center, Amman, Jordan, briefly comments on the challenge of early referral for hematopoietic stem cell transplantation (SCT) in pediatric patients with non-malignant hematological disorders, and how this is being addressed. This interview took place at the 51st Annual Meeting of the EBMT in Florence, Italy.

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Transcript

I think for the non-malignant conditions, it’s very challenging for these patients to come early to be referred to transplant centers. So the longer they wait before coming to the transplant center, the more complications, for example, more transfusion requirements and more organ overloads. And that makes the likelihood of the success of the transplant less and the mortality will be more, and in such cases, these patients will need to be transplanted using reduced intensity transplant, for example...

I think for the non-malignant conditions, it’s very challenging for these patients to come early to be referred to transplant centers. So the longer they wait before coming to the transplant center, the more complications, for example, more transfusion requirements and more organ overloads. And that makes the likelihood of the success of the transplant less and the mortality will be more, and in such cases, these patients will need to be transplanted using reduced intensity transplant, for example. And the way around this is now we’re working with the primary and secondary healthcare sectors to raise awareness about these diseases such as thalassemia needs to be referred early to transplant rather than later in order to avoid the complication, the graft failure, the organ damage as well. 

 

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