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ASH 2023 | Real-world outcomes of liso-cel therapy in R/R DLBCL

Peter Riedell, MD, University of Chicago Medicine, Chicago, IL, discusses a real-world analysis of outcomes for patients with relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL) treated with lisocabtagene maraleucel (liso-cel). In this patient population, who had a median of three prior lines of therapy and significant comorbidities, liso-cel was associated with favorable safety and efficacy outcomes that were comparable to those achieved in the TRANSCEND-NHL-001 trial (NCT02631044). This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Consultancy: AbbVie, Genmab, ADC Therapeutics, Pharmacyclics, Novartis, BMS, Kite/Gilead, Nurix Therapeutics, Nektar Therapeutics, Takeda, Intellia Therapeutics, Sana Biotechnology, BeiGene, Janssen, CVS Caremark; Speakers Bureau: Kite/Gilead; Honoraria: Novartis; Research Funding: BMS, Kite/Gilead, Novartis, MorphoSys, CRISPR Therapeutics, Calibr, Xencor, Fate Therapeutics, Tessa Therapeutics.