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ASH 2025 | The CaDAnCe-104 trial of BGB-16673 in combination with other agents in R/R B-cell malignancies

Chan Cheah, MBBS, FRACP, FRCPA, DMSc, Linear Clinical Research and Sir Charles Gairdner Hospital, Perth, Australia, discusses the CaDAnCe-104 trial (NCT06634589), an ongoing, open-label, phase Ib/II study of BTK degrader BGB-16673 in combination with other agents in patients with relapsed/refractory (R/R) B-cell malignancies. Dr Cheah highlights that the study involves multiple sub-studies, including combinations with zanubrutinib, sonrotoclax, glofitamab, and mosunetuzumab. This interview took place at the 67th ASH Annual Meeting and Exposition, held in Orlando, FL.

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