So to me, the optimal management for CLL is based on the individual characteristics of the patients. So we really need to take a deep definition of what are their prognostic factors. And then for patients that have favorable prognostic factor, I feel that many of the combinations that I mentioned before are going to be excellent in giving good, long lasting results with finite therapy. However, it is also important to identify the patients that have less favorable features for which we need to do a treatment that is going to be based on quality of response and depth of response...
So to me, the optimal management for CLL is based on the individual characteristics of the patients. So we really need to take a deep definition of what are their prognostic factors. And then for patients that have favorable prognostic factor, I feel that many of the combinations that I mentioned before are going to be excellent in giving good, long lasting results with finite therapy. However, it is also important to identify the patients that have less favorable features for which we need to do a treatment that is going to be based on quality of response and depth of response. And those are patients where we may need to extend treatment longer than the standard two years that has been, you know, one of the longest therapy done for finite duration.