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ASH 2024 | A Phase II trial of loncastuximab tesirine in previously treated Waldenström’s macroglobulinemia

Jorge Castillo, MD, Dana-Farber Cancer Institute, Boston, MA, outlines the promising results of a Phase II trial (NCT05190705) of the antibody-drug conjugate (ADC) loncastuximab tesirine in patients with previously treated Waldenström’s macroglobulinemia (WM). Dr Castillo highlights that this proof-of-concept study, conducted through the WM-NET network, has shown an encouraging efficacy rate at the interim analysis, with the majority of patients responding to the treatment. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.

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