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ASH 2023 | The addition of venetoclax to HMAs for the treatment of CMML: a retrospective PSM analysis

Douglas Tremblay, MD, Icahn School of Medicine at Mount Sinai, New York, NY, discusses the findings of a retrospective analysis of data from four academic centers, which aimed to compare the response rates and survival outcomes of patients with chronic myelomonocytic leukemia (CMML) treated with hypomethylating agents (HMA) with or without venetoclax. Using a propensity score-matched (PSM) analysis, the addition of venetoclax to treatment regimens was found to improve response rates of patients but conferred no benefit to survival outcomes. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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