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EHA 2024 | CD20/CD3 bispecific antibodies in R/R DLBCL: glofitamab and epcoritamab

Chris Fox, MBChB(Hons), MRCP, FRCPath, University of Nottingham, Nottingham, UK, discusses the role of CD20/CD3 bispecific antibodies in the treatment of relapsed/refractory (R/R) diffuse large B-cell lymphoma (DLBCL). Epcoritamab and glofitamab are currently utilized in third-line therapy for patients who have relapsed post-CAR-T or are ineligible, achieving complete response (CR) rates of up to 40%. This interview took place at the 29th Congress of the European Hematology Association (EHA) in Madrid, Spain.

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Disclosures

Consultancy/advisory boards: AbbVie, AstraZeneca, Atarabio, BMS, GenMab, Gilead/Kite, Incyte, Janssen, Lilly, Morphosys, Ono, Roche, SERB, SOBI, Takeda; Educational activities: AbbVie, Kite/Gilead, Incyte, Janssen, Roche, Takeda, SERB; Travel: Roche, Kite/Gilead; Research funding: BeiGene, AbbVie/GenMab.