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IMS 2024 | The genomic landscape of IgM MGUS & stable vs progressive asymptomatic WM

Tina Bagratuni, PhD, National and Kapodistrian University of Athens, Athens, Greece, discusses a study focusing on the genomic landscape of IgM monoclonal gammopathy of undetermined significance (MGUS) and asymptomatic Waldenström’s macroglobulinemia (WM). The study analyzed both stable and progressive asymptomatic patients, identifying specific genomic features, such as higher mutation burdens and CNV events, in those who progressed to symptomatic disease. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.

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