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EHA 2025 | Validating the ELN genetic risk classification in patients with AML treated with aza-ven

In this video, Juan Miguel Bergua-Burgues, MD, Hospital San Pedro de Alcantara, Cáceres, Spain, briefly comments on the validation of the European Leukemia Net (ELN) 2024 genetic risk classification for older patients with acute myeloid leukemia (AML) treated with the hypomethylating agent azacitidine (aza) plus venetoclax (ven). This interview took place at the 30th Congress of the European Hematology Association (EHA) in Milan, Italy.

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Transcript

This is a validation of the European Leukemia Net about the risk stratification in patients treated with aza-ven in older patients. We see that the European Leukemia Net can classify this type of patients in three groups. I think that there’s a work in progress about this type of comparison of the European Leukemia Net classification and the new classification of the European Leukemia Net about the classification with rungs and the new scale of mutation about TP53 and KRAS mutation...

This is a validation of the European Leukemia Net about the risk stratification in patients treated with aza-ven in older patients. We see that the European Leukemia Net can classify this type of patients in three groups. I think that there’s a work in progress about this type of comparison of the European Leukemia Net classification and the new classification of the European Leukemia Net about the classification with rungs and the new scale of mutation about TP53 and KRAS mutation. But we think that we support the conclusion of the classification of the European Leukemia Net in order to classify the risk of the patients treated with aza-ven.

 

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