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ERIC 2024 | CLL in Taiwan: prevalence, pathogenesis, and clinical practice

Shang-Ju Wu, MD, PhD, National Taiwan University Hospital, Taipei, Taiwan, discusses the prevalence and clinical practice of chronic lymphocytic leukemia (CLL) in Taiwan, highlighting an increasing incidence rate over the past two decades. He notes distinct molecular epidemiological characteristics of CLL in Taiwan compared to Caucasian populations, and emphasizes the differences in clinical practice due to a smaller patient population and variations in the medical care system. This interview took place at the 2024 European Research Initiative on CLL (ERIC) Meeting in Barcelona, Spain.

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Transcript

First of all, I will very briefly introduce what we have done with the basic research and clinical epidemiology research here in Taiwan. The conclusion should be that we have identified, although as everybody here is aware that CLL is much less prevalent in Asia, including Taiwan. But actually in the passing maybe 20 years, the incidence rate is going up continuously. So I think this disease will become more and more important here in this region...

First of all, I will very briefly introduce what we have done with the basic research and clinical epidemiology research here in Taiwan. The conclusion should be that we have identified, although as everybody here is aware that CLL is much less prevalent in Asia, including Taiwan. But actually in the passing maybe 20 years, the incidence rate is going up continuously. So I think this disease will become more and more important here in this region. On the other hand, we also identify some, let’s say, molecular epidemiology patterns, characteristics that occurs in Taiwan that is different from that in the Caucasians or in the US or in the EU. And in terms of that, we majorly identify that we have much less, let’s say, major stereotypes of CLL patients in our population. I believe this finding will point out the pathogenesis of CLL, especially in terms of the different epidemiology between the two populations. But in addition to this, my major focus will discuss the clinical practice in Taiwan. Because of the small patient population, as well as the differences in medical care systems, there are quite some differences between the clinical practice to deal with CLL patients here in this region. I will briefly introduce what we are doing, what the major gap we have had here in this region.

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