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EHA 2026 | IDH1-targeted therapy continues to reshape AML treatment

Agnieszka Wierzbowska, MD, PhD, Medical University of Lodz, Lodz, Poland, discusses the evolving treatment landscape for IDH1-mutated acute myeloid leukemia (AML). She reviews the impact of ivosidenib-based therapy, highlights promising early results from triplet combinations with venetoclax and azacitidine, and explains how ongoing Phase III studies could further redefine the standard of care for patients unfit for intensive chemotherapy. This interview took place at the 31st Congress of the European Hematology Association (EHA) in Stockholm, Sweden.

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