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ASH 2021 | Diagnostic tools for AML

Curtis Lachowiez, MD, The University of Texas MD Anderson Cancer Center, Houston, TX, outlines the tools and platforms used for the diagnosis of acute myeloid leukemia (AML). Morphological assessment of the bone marrow is the main diagnostic strategy used to identify the type of leukemia a patient has. As technology has advanced, several additional tools are used to provide more detail on a patient’s disease. Cytogenetic and molecular genetic analyses are conducted using fluorescence in situ hybridization (FISH), next-generation sequencing, and flow cytometry. Dr Lachowiez explains the extra information that can be provide by the identification of prognostic and predictive genetic changes using these techniques. This interview took place at the 63rd ASH Annual Meeting and Exposition congress in Atlanta, GA.