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IMS 2024 | The key unmet needs in the frontline and R/R setting in amyloidosis

Pedro Vianna, MD, Dana-Farber Cancer Institute, Boston, MA, emphasizes the importance of early diagnosis for patients with amyloidosis, which is preceded by monoclonal gammopathy of unknown significance (MGUS), and advocates for a multidisciplinary approach to manage the various organ systems affected by the disease. In relapsed/refractory (R/R) cases, Dr Vianna highlights the need for more precise criteria to define hematological relapse and suggests that novel treatments, such as venetoclax, bispecific antibodies, or anti-fibrillary therapies, show promise for treating these patients. This interview took place at the 21st International Myeloma Society (IMS) Annual Meeting, held in Rio de Janeiro, Brazil.

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