Tamar Tadmor, MD, Bnai Zion Medical Center, Haifa, Israel, comments on recent developments in the treatment of elderly patients with Richter’s transformation (RT), sharing results from a Phase II trial (NCT04939363) using an experimental regimen consisting of fixed-duration obinutuzumab, ibrutinib, and venetoclax. Dr Tadmor highlights the study’s unique elderly cohort, with a median age of 76, in addition to the rapid ramp-up of venetoclax introduction, and further summarizes key results. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.
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