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ASH 2024 | Phase II study of fixed-duration obinutuzumab, ibrutinib & venetoclax in elderly patients with RT

Tamar Tadmor, MD, Bnai Zion Medical Center, Haifa, Israel, comments on recent developments in the treatment of elderly patients with Richter’s transformation (RT), sharing results from a Phase II trial (NCT04939363) using an experimental regimen consisting of fixed-duration obinutuzumab, ibrutinib, and venetoclax. Dr Tadmor highlights the study’s unique elderly cohort, with a median age of 76, in addition to the rapid ramp-up of venetoclax introduction, and further summarizes key results. This interview took place at the 66th ASH Annual Meeting and Exposition, held in San Diego, CA.

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