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ASH 2023 | The role of complement activation in complications of sickle cell disease

Lucia De Franceschi, MD, University of Verona, Verona, Italy, outlines the role of complement activation in sickle cell disease (SCD) complications. Linked to a more severe phenotype, complement activation emerges as a promising therapeutic target currently under evaluation in three ongoing clinical trials. This interview took place at the 65th ASH Annual Meeting and Exposition, held in San Diego, CA.

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Disclosures

Research Funding: Bristol Myers Squibb, Agios
Board of Directors/Advisory Committee: F. Hoffmann-La Roche Ltd, Basel