ICML 2023 | Update on MB-106: CD20 CAR-T therapy for follicular lymphoma
Mazyar Shadman, MD, Fred Hutchinson Cancer Research Center, Seattle, WA, comments on the results of a study evaluating MB-106, a third-generation CD20-directed CAR-T therapy for the outpatient treatment of follicular lymphoma (FL). Dr Shadman notes high efficacy rates, with no reports of high-grade cytokine release syndrome (CRS), and no immune effector cell-associated neurotoxicity syndrome (ICANS).
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Disclosures
MEI Pharma: Consultancy; Fate Therapeutics: Consultancy; Bristol Myers Squibb: Consultancy, Research Funding; TG Therapeutics: Consultancy, Research Funding; Innate Pharma: Consultancy; Epi Lilly: Consultancy; Adaptimmune: Consultancy; AstraZeneca: Consultancy, Research Funding; Epizyme: Consultancy; Mustang Bio: Consultancy, Research Funding; Beigene: Consultancy, Research Funding; Genentech: Consultancy, Research Funding; Regeneron: Consultancy; Merck: Consultancy; Adaptive Biotechnologies: Consultancy; Morphosys/Incyte: Consultancy, Research Funding; Pharmacyclics: Consultancy, Research Funding; Sound Biologics: Consultancy; Kite Pharma: Consultancy; Abbvie: Consultancy, Research Funding; Atara Biotherapeutic: Consultancy, Research Funding; Celgene, a BMS Company: Research Funding; Gilead: Research Funding; Sunesis: Research Funding; Genmab: Research Funding.
