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IWWM-12 2024 | MYD88-mutated IgM monoclonal gammopathies: chromatin accessibility and transcription factor dynamics
David Moreno, MD, PhD, Hospital Clínic de Barcelona, Barcelona, Spain, discusses research using single-cell RNA sequencing and ATAC-seq to understand the chromatin accessibility and transcription factor dynamics in MYD88-mutated IgM monoclonal gammopathies. The study emphasizes the potential of targeting specific transcription factors, particularly from the POU family, for the treatment of these diseases. This interview took place at the 12th International Workshop on Waldenström’s Macroglobulinemia (IWWM-12) in Prague, Czech Republic.
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